Low-intensity pulsed ultrasound enhances angiogenesis and ameliorates contractile dysfunction of pressure-overloaded heart in mice
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چکیده
منابع مشابه
Low-intensity pulsed ultrasound enhances angiogenesis and ameliorates contractile dysfunction of pressure-overloaded heart in mice
INTRODUCTION Chronic left ventricular (LV) pressure overload causes relative ischemia with resultant LV dysfunction. We have recently demonstrated that low-intensity pulsed ultrasound (LIPUS) improves myocardial ischemia in a pig model of chronic myocardial ischemia through enhanced myocardial angiogenesis. In the present study, we thus examined whether LIPUS also ameliorates contractile dysfun...
متن کاملLow-Intensity Pulsed Ultrasound Enhances Angiogenesis and Ameliorates Left Ventricular Dysfunction in a Mouse Model of Acute Myocardial Infarction.
OBJECTIVE Left ventricular (LV) remodeling after acute myocardial infarction still remains an important issue in cardiovascular medicine. We have recently demonstrated that low-intensity pulsed ultrasound (LIPUS) therapy improves myocardial ischemia in a pig model of chronic myocardial ischemia through enhanced myocardial angiogenesis. In the present study, we aimed to demonstrate whether LIPUS...
متن کاملLow-Intensity Pulsed Ultrasound Induces Angiogenesis and Ameliorates Left Ventricular Dysfunction in a Porcine Model of Chronic Myocardial Ischemia
BACKGROUND Although a significant progress has been made in the management of ischemic heart disease (IHD), the number of severe IHD patients is increasing. Thus, it is crucial to develop new, non-invasive therapeutic strategies. In the present study, we aimed to develop low-intensity pulsed ultrasound (LIPUS) therapy for the treatment of IHD. METHODS AND RESULTS We first confirmed that in cu...
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In order to study the effect of ultrasound (US) on bone healing, a complete transverse fracture was made in the right radius of adult male rabbits by a cutter. 52 rabbits were used: group I. control (n= 17): group 2. test (n:=: 15): group 3, intact (n= I) and group 4 (n= 12) who were examined only for evaluation of the cutter effects in detail. 7 animals were operated with a Gigli saw. The ...
متن کاملLow Intensity Pulsed Ultrasound (LIPUS)
The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0185555